01608nas a2200265   4500000000100000008004100001260001300042653001100055653001100066653001400077653001200091653001300103653003900116653001400155653004000169100001500209700001600224245004100240856004100281300000900322490000700331050001500338520097500353022001401328       1982                            d  c1982 Mar10aFemale10aHumans10aLactation10aleprosy10aNeuritis10aPeripheral Nervous System Diseases10aPregnancy10aPregnancy Complications, Infectious1 aDuncan M E1 aPearson J M00aNeuritis in pregnancy and lactation.  uhttp://ila.ilsl.br/pdfs/v50n1a04.pdf  a31-80 v50  aDUNCAN19823 a<p>One hundred and forty-six women were studied during and after 153 pregnancies (31 healthy contacts: 34 pregnancies; 115 leprosy patients: 119 pregnancies). One healthy contact and 51 leprosy patients developed neuritis during the study period. All leprosy patients, including those who were considered to be cured and had stopped treatment, were at risk. Neuritis was accompanied by Type 1 and Type 2 lepra skin reactions and/or deterioration of the patients' leprosy status; this was particularly the case when neuritis was associated with nerve pain or tenderness (overt neuritis). Neuritis without nerve pain or tenderness (silent neuritis), preceded by the complaint of "rheumatism" and the clinical finding of enlarged peripheral nerves, was seen more frequently than overt neuritis (48:37 episodes). Insidious silent neuritis with loss of sensory and motor function during lactation was a particularly dangerous and hitherto undescribed risk of pregnancy.</p>
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