01774nas a2200337   4500000000100000008004100001260000900042653001000051653000900061653001200070653001500082653001100097653003500108653001100143653002000154653000900174653000900183653001600192653001800208653001800226653003000244100001300274700001500287700001400302700001700316245014700333300001800480490000800498520091600506022001401422       1981                            d  c198110aAdult10aAged10aAnimals10aAntibodies10aFemale10aFluorescent Antibody Technique10aHumans10aLeukocyte Count10aMale10aMice10aMiddle Aged10aSkin Diseases10aT-Lymphocytes10aT-Lymphocytes, Regulatory1 aFulton R1 aThivolet J1 aGarcier F1 aGaucherand M00a[Sub-populations of T helper suppressor lymphocytes in diverse dermatoses using monoclonal antibodies. Preliminary results (author's transl)].  a243-6, 249-500 v1083 a<p>The total T lymphocyte and T cell subsets were counted in various dermatoses by indirect immunofluorescence using the monoclonal antibodies OKT3, OKT4, OKT8 which distinguish all peripheral T cells, helper T cells and suppressor T cells respectively. In particular, 7 cases of the Sézary syndrome and 7 cases of mycosis fungoides were studied. In addition, 42 other patients with diverse dermatoses such as psoriasis, atopic eczema, bullous disorders, sarcoidosis, lupus erythematosus and leprosy were studied and compared to 20 healthy controls. There was no significant increase in the total T cell percentage in the ratio of helper to suppressor lymphocytes in the Sézary syndrome with a normal balance in mycosis fungoides. Among the other dermatoses only atopic eczema showed a significant increase in the helper/suppressor ratio suggesting an imbalance of T cell subpopulations in this condition.</p>  a0151-9638