01328nas a2200265   4500000000100000008004100001260001300042653001400055653002600069653001400095653001100109653001200120653000900132653001600141653001500157653001600172653001700188100002300205700002200228245006600250300001000316490000700326520071500333022001401048       1981                            d  c1981 Jan10aCytoplasm10aForeign-Body Reaction10aHepatitis10aHumans10aleprosy10aLung10aLymph Nodes10aMuramidase10aSarcoidosis10aTuberculosis1 aBlennerhassett J B1 aPapadimitriou J M00aMuramidase content of cells in human granulomatous reactions.  a101-90 v133 a<p>The muramidase content of reactive cells in the lesions of human foreign body reactions, lepromatous and tuberculoid leprosy, sarcoidosis, tuberculosis, and granulomatous hepatitis, was assessed using specific anti-human muramidase antiserum and a peroxidase-anti-peroxidase marker system. Epithelioid and giant cells in sarcoidosis, tuberculosis, granulomatous hepatitis, and tuberculoid leprosy all showed the presence of muramidase in their cytoplasm. The muramidase content of macrophages in foreign body reactions and lepromatous leprosy varied and most multinucleate cells in these lesions gave a negative reaction. Possibly varying rates of muramidase secretion may account for these differences.</p>  a0031-3025