01395nas a2200229   4500000000100000008004100001260001300042653001500055653001000070653002100080653001100101653001200112653000900124653001200133100001500145700001100160245007400171300000900245490000700254520089000261022001401151       1979                            d  c1979 Jan10aAdolescent10aAdult10aElectromyography10aHumans10aleprosy10aMale10aMuscles1 aSébille A1 aGray F00aElectromyographic recording and muscle biopsy in lepromatous leprosy.  a3-100 v403 a<p>The aim of this study was to detect early muscular changes in lepromatous leprosy using simultaneously electromyography and muscle biopsy. In 13 subjects a single clinically normal muscle innervated by the popliteal nerve was studied. Three were found to be normal. All the others were electromyographically denervated. Histopathologic findings included only 3 cases of fascicular atrophy. In 8 cases inflammatory nodules were observed in the connective tissue of the muscle and acid-fast bacilli were present in Virchow cells in 5. In only one patient were intact acid-fast bacilli found in muscle cells. It was concluded that electromyography was the better method of detecting early denervation, while muscle biopsy was the better examination to detect "lepromatous myositis". In practice these techniques are complementary in the study of muscle data in lepromatous leprosy.</p>  a0022-510X