01353nas a2200229   4500000000100000008004100001260001300042653001100055653001400066653001200080653001100092653003000103100001700133700001900150245011000169856005900279300001100338490000700349050003200356520072100388022001401109       1993                            d  c1993 Sep10aHumans10aIncidence10aleprosy10aMalawi10aWorld Health Organization1 aBoerrigter G1 aPonnighaus J M00aDoes the introduction of WHO-MDT influence trends in the incidence of leprosy?--the Malaŵian experience.  uhttp://leprev.ilsl.br/pdfs/1993/v64n3/pdf/v64n3a06.pdf  a227-350 v64  aInfolep Library - available3 a<p>There has been an average annual decline in detection rates of all types of leprosy in Malaŵi of around 11.6% between 1977 and 1991. There was no obvious acceleration or slowing down of this decline following the introduction of WHO/MDT in 1983-84. Disability ratios stayed at the same level of about 11% during the 15 years covered by this paper suggesting that patients did not self-report earlier after 1983-84 which might have masked an underlying accelerated decline in detection rates. Thus it is concluded that the influence of WHO/MDT on the pattern of leprosy over a period of time, in a country like Malaŵi, is so far not noticeably different from any influence dapsone monotherapy might have had.</p>  a0305-7518