01424nas a2200265   4500000000100000008004100001260001300042653002800055653001000083653003900093653002800132653001400160653001100174653001200185653000900197653001200206653000900218653001800227100001200245245002800257300001000285490000700295520084200302022001401144       1977                            d  c1977 Jul10aAdrenal Cortex Hormones10aAdult10aAfrican Continental Ancestry Group10aDiagnosis, Differential10aGranuloma10aHumans10aleprosy10aMale10aNigeria10aSkin10aSkin Diseases1 aRogge T00a[Granuloma multiforme].  a375-70 v283 a<p>A case of granuloma multiforme is reported. Granuloma multiforme has been seen so far only in blacks from Nigeria or East Africa. The disease does not affect children and adolescents. Common sites of infection are arms, chest, back, neck, and head. The differential diagnosis is tuberculoid leprosy and granuloma anulare. Granuloma multiforme also shows similarity to that of granuloma anulare or, if more of a tuberculoid nature, to that of sarcoidosis or that of granulomatosis disciformis chronica et progressiva Miescher. The etiology of granuloma multiforme is unknown. It may respond to intralesional corticosteroid therapy or show involution following a diagnostic biopsy. In the reported case response to intralesional corticosteroid suspension and topical application of dimethyldiphenylendisulfide was very satisfactory.</p>  a0017-8470