01448nas a2200301 4500000000100000008004100001260001300042653001500055653001000070653002800080653001100108653001100119653001800130653002800148653001200176653000900188653001600197653001800213100001500231700001600246700001400262700001300276245004100289300001100330490000700341520078400348022001401132 1977 d c1977 Sep10aAdolescent10aAdult10aDiagnosis, Differential10aFemale10aHumans10aLeishmaniasis10aLeishmaniasis, Visceral10aleprosy10aMale10aMiddle Aged10aSkin Diseases1 aGirgla H S1 aMarsden R A1 aSingh G M1 aRyan T J00aPost-kala-azar dermal leishmaniasis. a307-110 v973 a

Ten patients with post-kala-azar dermal leishmaniasis (2 females, 8 males-aged 17-47 years) are described. Two of them had macular lesions in which very few Leishman-Donovan bodies were seen and who responded well to treatment with stibophen. Five patients had both macular and nodular lesions, Leishman-Donovan bodies being present in nodules but not in macules. Treatment with stibophen caused partial regression of nodules. Nodular lesions were found in three patients, who did not have macules. They contained numerous Leishman-Donovan bodies and treatment produced only temporary improvement. The variable response to treatment with stibophen may have been due to differences in parasitic load. The difficulty in distinguishing this disease from leprosy is discussed.

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