01426nas a2200325   4500000000100000008004100001260001400042653001200056653001300068653001400081653001300095653002500108653001800133653001200151653000900163653001400172653000800186100001600194700001200210700001200222700001700234700001700251700001200268245010600280856007900386300001600465490000700481050002000488520059200508       2007                            d  c2007/09//10aTherapy10aSyndrome10aSecondary10aPatients10aMycobacterium leprae10aMycobacterium10aleprosy10aIris10aInfection10aHIV1 aMartiniuk F1 aRao S D1 aRea T H1 aGlickman M S1 aGiovinazzo J1 aRom W N00aLeprosy as Immune Reconstitution Inflammatory Syndrome in HIV-positive persons : letter to the editor  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857291/pdf/07-0301_finalL.pdf  a1438 - 14400 v13  aMARTINIUK 2007A3 a<p>More than two decades ago, when HIV was first detected, many investigators predicted the rise of leprosy secondary to opportunistic infection. Recently the phenommenon of immune reconstitution inflammatory syndrome (IRIS), or leprosy reversal respons, has received attraction. IRIS often occurs secondary to initiating highly active antiretroviral therapy (HAART). The first indications of an interaction between HIV an Mycobacterium leprae occurred only recently, with the identification of IRIS after initiation of HAART in patients with HIV and previously undetected leprosy.</p>