01871nas a2200361 4500000000100000008004100001260001300042653003600055653003600091653001800127653002200145653002400167653001400191653001100205653001200216653003100228653000900259653001600268653002000284653002200304653001900326653002200345100001900367700002300386700002100409700001800430245009200448856006500540300001100605490000700616520087200623022001401495 2010 d c2010 Nov 10 aAntimetabolites, Antineoplastic 10 aCell Transformation, Neoplastic 10 aDeoxycytidine 10 aDiagnostic Errors 10 aDisease Progression 10 aGranuloma 10 aHumans 10 aleprosy 10 aMagnetic Resonance Imaging 10 aMale 10 aMiddle Aged 10 aMuscle Weakness 10 aMycosis Fungoides 10 aSkin Neoplasms 10 aTreatment Outcome 1 aSiriphukpong S 1 aPattanaprichakul P 1 aSitthinamsuwan P 1 aKaroopongse E 00 aGranulomatous mycosis fungoides with large cell transformation misdiagnosed as leprosy. uhttp://www.mat.or.th/journal/files/Vol93_No.11_1321_6270.pdf a1321-6 0 v93 3 aBACKGROUND: Granulomatous mycosis fungoides is an unusual histopathological variant of cutaneous T-cell lymphoma without clinical distinction from classic mycosis fungoides. Symptoms associated with peripheral nerve involvement have rarely been reported in the literature.
CASE REPORT: The authors described a case of granulomatous MF stage IIB with large cell transformation who initially presented with leprosy-like condition and chronic left peroneal neuropathy The patient received six courses ofgemcitabine with greater than 90% improvement of skin lesions. The rest of the lesions were successfully treated with local electron beam radiation.
CONCLUSION: Granulomatous MF with neuropathy can be clinically misdiagnosed if there is no histopathological and immunohistochemical finding to support the diagnosis of lymphoma.
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