01388nas a2200265   4500000000100000008004100001260001300042653001000055653002900065653002800094653001500122653001100137653001200148653000900160653001900169100001800188700001400206700001400220700001800234245009600252300001000348490000600358520074400364022001401108       2010                            d  c2010 Dec10aAdult10aCarcinoma, Squamous Cell10aDiagnosis, Differential10aFoot Ulcer10aHumans10aleprosy10aMale10aSkin Neoplasms1 aVenkatswami S1 aAnandan S1 aKrishna N1 aNarayanan C D00aSquamous cell carcinoma masquerading as a trophic ulcer in a patient with Hansen's disease.  a163-50 v93 a<p>Nonhealing trophic ulcers in leprosy are a common phenomenon, but acute malignant transformations of the same are relatively rare. This study reports on a 35-year-old man previously treated for Hansen's disease with a squamous cell carcinoma involving the right foot with rapid lymphatic spread. He was being treated as a benign trophic ulcer for more than 12 months until he started developing huge inguinal lymph nodes and the ulcer rapidly increased in size. Squamous cell carcinomas are known to occur in ulcers of considerable duration but such rapid growth in such a short duration and rapid lymphatic spread is unusual in Marjolin's ulcer as the lymphatics are usually destroyed because of previous inflammation and scarring.</p>  a1552-6941