02039nas a2200337   4500000000100000008004100001260001600042653001500058653001000073653001100083653001100094653001400105653001000119653002500129653000900154653001600163653002500179653000900204653001600213100001700229700001100246700001400257700001100271700001300282245007400295856006400369300001100433490000600444520123700450022001401687       2011                            d  c2011 Mar 0210aAdolescent10aAdult10aFemale10aHumans10aIncidence10aIndia10aLeprosy, lepromatous10aMale10aMiddle Aged10aMycobacterium leprae10aSkin10aYoung Adult1 aMendiratta V1 aJain A1 aChander R1 aKhan A1 aBarara M00aA nine-year clinico-epidemiological study of Histoid Hansen in India.  uhttp://www.jidc.org/index.php/journal/article/view/21389593  a128-310 v53 a<p><b>INTRODUCTION: </b>Histoid Hansen is rare but a well-defined entity with specific clinical, histopathological, and bacteriological features. The incidence has been reported to vary from 1-2% amongst total leprosy patients.</p><p><b>METHODOLOGY: </b>We performed a retrospective analysis of the records of patients identified as histoid Hansen on the basis of clinico-histopathological criteria, who attended the Hansen clinic from 2000-2009.</p><p><b>RESULTS: </b>A total of 962 leprosy patients attended the Hansen clinic from 2000-2009, and of these, 11 (1.14%) were diagnosed as histoid Hansen. The youngest patient on record was 14 years of age. Nearly 70% of the patients were untreated and the rest were on multidrug therapy (MDT) before development of histoid lesions. Three patients showed Erythema nodusum leposum (ENL) reaction.</p><p><b>CONCLUSION: </b>India has achieved elimination of leprosy, but new cases of histoid are still recorded with the same incidence rate. Reactions are not uncommon in such forms, and may be a transition phase to manifest lepromatous leprosy. A thorough knowledge and early detection is needed for this uncommon variant of leprosy which can pose a threat to our elimination drive.</p>  a1972-2680