00792nas a2200145 4500000000100000008004100001260001300042100001200055245004100067856005700108300001000165490000600175520045100181022001400632 2011 d c2011 Jul1 aGrace M00aAn unusual case of dapsone syndrome. uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481807/ a88-900 v23 a
Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report an unusual case of dapsone hypersensitivity, manifesting as bone marrow suppression and peripheral pancytopenia in addition to fever, rash, and hepatosplenomegaly.
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