01487nas a2200217 4500000000100000008004100001653001400042653001200056653002700068653002000095100001500115700001400130700001300144700001400157245005400171856007800225300001200303490000700315050001700322520093000339 2012 d10aTreatment10aleprosy10aGranulomatous diseases10aEarly detection1 aKhondker L1 aWahab M A1 aKhan M S1 aHazra S C00aLeprosy: need early detection and early treatment uhttp://www.banglajol.info/index.php/MEDTODAY/article/viewFile/14116/10093 a44 - 470 v24 aKHONKER 20123 aLeprosy is the most ancient bacterial disease in the history of mankind. It remains still public health problem in the countries where it is endemic. Leprosy (Hansen’s disease) is a chronic infectious disease which is diagnosable and curable if recognized early and treated adequately. The infectious agent of leprosy is Mycobacterium leprae which is only bacteria to infect peripheral nerves. Leprosy is characterized by a variety of abnormal immune response. It depends on the integrity of the host’s specific CMI response to the M. leprae and it may be genetically determined. Antileprotic multidrugs therapy (MDT) as recommended by WHO is now the standard and accepted method for leprosy control. Leprosy can not be completely rooted out with physicians, control offices, leprosaria and propaganda; it will disappear when the economic and cultural factors change, because leprosy is the thermometer of civilization.