00636nas a2200157   4500000000100000008004100001260001600042100001600058700001300074245004200087300001000129490000700139050001900146520029900165022001400464       2013                            d  c2013 Apr 171 aDesvignes L1 aErnst JD00aTaking sides: interferons in leprosy.  a377-80 v13  aDESVIGNES 20133 a<p>In a recent Science paper, Teles et al. (2013) show that type I and II interferons (IFNs) are reciprocally expressed in the polar immune forms of leprosy, with type I IFNs inducing IL-10 that interferes with the antimycobacterial effects of type II IFNs (IFNγ) at the site of infection.</p>  a1934-6069