01937nas a2200241   4500000000100000008004100001260001300042100001200055700001400067700001500081700001700096700001300113700001500126700001900141700001500160700001400175700001300189245013500202300001000337490000700347520132700354022001401681       2013                            d  c2013 Sep1 aSzabo I1 aKulkova N1 aSokolova J1 aMikolasova G1 aSuvada J1 aKalavska A1 aDobrodenkova S1 aMateicka F1 aKafkova J1 aNkonwa I00aNeurologic complications and sequellae of infectious diseases in Uganda and Kenya: Analysis of 288 cases from two rural hospitals.  a28-310 v343 a<p><b>OBJECTIVE: </b>Many infections occurring in area of Sub-Saharan Africa are associated with more or less serious neurologic symptoms or complications. The aim of this study was to assess the incidence of selected infectious diseases in the equatorial part of Uganda and Kenya and to monitor potential neurological complications of these infections.</p><p><b>METHODS: </b>The study was performed for May - August 2008. Patients suffering from cerebral malaria, AIDS, meningitis, typhoid, tuberculosis (TB), syphilis, leprosy, and trypanosomiasis patients were enrolled. Besides of standard examination, lumbar puncture (LP) and cerebrospinal fluid (CSF) examination was performed, and the occurrence of neurological disorders and sequellae was recorded and assessed.</p><p><b>RESULTS: </b>Altogether 288 patients with neurological manifestation were enrolled. Malaria was the most prevalent disease in this study (102 cases, 35.42%), followed by typhoid (47 cases, 16.2%) and meningitis (38 cases, 13.2%). Leprosy and trypanosomiasis were only rarely detected (2.3% and 1.4%, respectively).</p><p><b>CONCLUSION: </b>In malaria and HIV hyper-endemic area of rural Uganda, cerebral malaria is the leading tropical neuroinfection. Also, meningitis is still frequent probably due to insufficient access to vaccination.</p>  a0172-780X