01134nas a2200181   4500000000100000008004100001653000900042653001200051653001000063653002400073100001400097700001300111245007800124856005500202300001200257050001700269520066600286       2013                            d10aZinc10aleprosy10aIndia10aAdenosine Deaminase1 aPradhan T1 aKumari S00aEffect of Zinc supplementation on Adenosine Deaminase activity in Leprosy  uhttp://medind.nic.in/ice/t13/i10/icet13i10p376.pdf  a376-380  aPRADHAN 20133 aSerum
Adenosine Deaminase (ADA) acts as marker of cellular immunity and its activity is found to be altered in various diseases in which there is a cell mediated immune response (CMI) including leprosy. The role of zinc is well established in the development and maintainence of immunocompetence and its supplementation activates the immune response in particular T-lymphocytes and monocytes in several ways. The aim of the study was planned to evaluate the effect of nutritional zinc supplementation on cell mediated immune response by investigating the pre and post intervention serum  ADA levels after oral zinc sulphate supplementation in leprosy patients.