01384nas a2200205   4500000000100000008004100001653001200042653002500054653001400079100001200093700001700105700001500122700001700137700001400154700001400168700001200182245004600194520092400240022001401164       2014                            d10aleprosy10aLucio’s phenomenon10adiagnosis1 aCuri PF1 aVillaroel JS1 aMigliore N1 aAlbertengo A1 aAquino ML1 aCeccato F1 aPaira S00aLucio's phenomenon: report of five cases.3 a<p>The different clinical forms of leprosy are mainly related to the variety of immunological responses to the infection. Several forms of lepromatous leprosy are recognized, including macular, nodular, and diffuse. Lucio's phenomenon is a rare but distinctive skin eruption seen in patients with diffuse lepromatous leprosy. The diffuse lesions of Lucio's phenomenon have a predilection for the extremities, can include nodules, and heal with atrophic stellate scars; histologically, a necrotizing vasculitis accompanied by a nonspecific inflammatory reaction may be seen. Because of its rarity and similarity with some manifestations of the rheumatic disease and other causes of vasculitis, Lucio's phenomenon may not be easily recognized, especially in non-endemic countries, which leads to confusing diagnosis and loss of time for treatment. We report five patients with vasculitis caused by Lucio's phenomenon.</p>  a1434-9949