02681nas a2200301   4500000000100000008004100001653001400042653001700056653002700073653002700100653001200127653001000139653001300149653001300162100002300175700001500198700001200213700001500225700001700240700001300257700001900270700001800289245011500307856005100422300001200473490000700485520188700492       2014                            d10aTreatment10aTransmission10aPaucibacillary leprosy10aMultibacillary leprosy10aleprosy10aIndia10aHospital10aChildren1 aSasidharanpillai S1 aBINITHA MP1 aRiyaz N1 aAMBOOKEN B1 aMARIYATH OKR1 aGeorge B1 aJANARDHANAN AK1 aSHERJEENA PVB00aChildhood leprosy: A retrospective descriptive study from Government Medical College, Kozhikode, Kerala, India  uhttps://leprosyreview.org/article/85/2/10-0110  a100-1100 v853 a<p>Objective: To assess the profile and describe the clinical presentations and complications of childhood leprosy in a tertiary care hospital in North Kerala, South India during 2003–2012 and to analyse any change in the age-sex profile and the clinical pattern of leprosy in children below the age of 15 years over the 10-year study period. Design: A retrospective descriptive study of children less than 15 years of age diagnosed with leprosy and registered for treatment in a tertiary care institution from 2003 to 2012. Demographic, clinical, investigative and Treatment data were collected using a pre-set proforma. Results: 138 (12·1%) of the total 1143 leprosy cases registered for treatment during the 10-year period were below 15 years of age. The 10-year study period witnessed a statistically insignificant decrease in the new childhood leprosy cases registered for treatment in our tertiary care institution. The majority of cases belonged to the 6–12 year age group (61·6%) with a male predominance. Borderline tuberculoid (BT) was the commonest clinical type (65·9%) followed by indeterminate leprosy (18·8%); 101 patients required paucibacillary (PB) and 37 needed multibacillary (MB) treatment. The number of patients requiring MB treatment showed a statistically significant increase and there was a significant decline in number of cases requiring PB treatment. During the entire study period no Type 2 lepra reaction was documented in patients below Hema 15 years and only two patients manifested Type 1 reaction. Ten (7·2%) out of the 138 patients were cases of relapse. There was a clear female predilection among relapse cases with the majority belonging to the adolescent age. Conclusions: Childhood leprosy still contributes to a significant proportion of the total case load denoting the continuing active horizontal transmission of leprosy.</p>