01488nas a2200253   4500000000100000008004100001653001700042653001200059653001700071653003000088100002100118700001600139700001500155700001800170700001300188700001600201700001300217245008800230856008000318300000700398490000700405520080800412022001401220       2014                            d10aMycobacteria10aleprosy10aTuberculosis10aErythema Nodosum Leprosum1 aParise-Fortes MR1 aLastória J1 aMarques SA1 aPutinatti MSA1 aStolf HO1 aMarques MEA1 aHaddad V00aLepromatous leprosy and perianal tuberculosis: a case report and literature review.  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150118/pdf/1678-9199-20-38.pdf  a380 v203 a<p>Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both mycobacterial infections are endemic.</p>  a1678-9199