01295nas a2200217 4500000000100000008004100001653003500042653001200077653001500089653001400104653002700118100001300145700001000158700001200168700001200180700001400192245007600206300000800282520077300290022001401063 2014 d10aHemorrhagic bullous dermatosis10aleprosy10aEnoxaparin10aTreatment10aIschemic heart disease1 aOzturk S1 aCan I1 aErden I1 aAkyol H1 aSolmaz OA00aEnoxaparin-induced hemorrhagic bullous dermatosis in a leprosy patient. a1-33 a
Abstract Enoxaparin is a low-molecular-weight heparin that has been used widely to prevent and treat thromboembolic disorders for at least 30 years. The most common adverse skin reactions to enoxaparin are ecchymosis and skin necrosis due to vasculitis, urticaria, angioedema and erythema. Side effects from heparin administration are rare and usually located at the injection site. However, recent reports have suggested that they can also occur at a distance from the site of injection. Moreover, the etiopathogenesis has not been fully explained. In this article, we present a case of hemorrhagic bullous dermatosis associated with enoxaparin for the treatment of ischemic heart disease that developed in a patient with a past history of lepromatous leprosy.
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