02196nas a2200289   4500000000100000008004100001653001900042653001200061653001300073653001300086100001200099700002100111700002200132700002000154700001500174700001300189700001500202700001500217700001200232700001600244245011400260856006800374300000700442490000700449520143600456022001401892       2014                            d10aLeprosy ulcers10aleprosy10aHospital10aEthiopia1 aRamos J1 aPérez-Tanoira R1 aGarcía-García C1 aPrieto-Pérez L1 aBellón MC1 aMateos F1 aTisisano G1 aYohannes T1 aReyes F1 aGórgolas M00aLeprosy ulcers in a rural hospital of Ethiopia: pattern of aerobic bacterial isolates and drug sensitivities.  uhttp://www.ann-clinmicrob.com/content/pdf/s12941-014-0047-z.pdf  a470 v133 a<p>BackgroundPlantar ulcers, which commonly occur in leprosy patients, tend to recur increasing physical disability. The aim of this study is to identify both the bacteriological profile of these ulcers and the antibiotic susceptibility of the isolated bacteria.Materials and methods68 leprosy patients with chronic ulcers attending the in-patient department of Gambo General Hospital, West Arsi, were included in this study. Proper sample collection, inoculation on culture media, and final identification using biochemical methods were undertaken.Results66 patients (97.1%) had a positive culture. A total of 81 microorganisms were isolated. Multiple organisms (two or more) were isolated in 15 (22.7% out of positive culture) patients. The main isolation was Proteus spp (30.9%), followed by Escherichia coli (21.0%), Staphylococcus aureus (18.5%) and Pseudomonas aeruginosa (9.9%). In the total number of the isolated bacteria, the antibiotics with less resistance were gentamicin (18.5%), fosfomycin (22.2%) cefoxitin (24.7%), ceftriaxone (25.9%) ciprofloxacin (25.9%), and amoxicillin-clavulanic acid (28.49%).ConclusionThe bacteriological study of plantar ulcers of leprosy patients revealed Enterobacteriaceae and S. aureus as the main pathogens involved in such infections. The results of this study may guide empirical therapy in a rural area hospital where culture and susceptibility testing facilities are scarce.</p>
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