01778nas a2200265   4500000000100000008004100001653000900042653001400051653002000065653003900085100001200124700001100136700001300147700001300160700001400173700001200187700001600199700001600215700001400231700001600245245009000261856007300351520107400424022001401498       2014                            d10aYaws10aTreatment10aSolomon islands10aNeglected tropical diseases (NTDs)1 aMarks M1 aVahi V1 aSokana O1 aPuiahi E1 aPavluck A1 aZhang Z1 aDalipanda T1 aBottomley C1 aMabey D C1 aSolomon A W00aMapping the epidemiology of yaws in the Solomon Islands: A cluster randomized survey.  uhttp://www.ajtmh.org/content/early/2014/11/24/ajtmh.14-0438.full.pdf3 a<p>Yaws, a non-venereal treponemal disease, is targeted for eradication by 2020 but accurate epidemiological data to guide control programs remain sparse. The Solomon Islands reports the second highest number of cases of yaws worldwide. We conducted a cluster randomized survey of yaws in two provinces of the Solomon Islands. One thousand four hundred and ninety-seven (1,497) children 5–14 years of age were examined. Clinical signs of active yaws were found in 79 children (5.5%), whereas 140 children (9.4%) had evidence of healed yaws lesions. Four hundred and seventy (470) (31.4%) children had a positive Treponema pallidum particle agglutination assay (TPPA). Two hundred and eighty-five (285) children (19%) had a positive TPPA and rapid plasma regain assay. Risk of yaws increased with age and was more common in males. The prevalence of yaws at village level was the major risk factor for infection. Our findings suggest the village, not the household, should be the unit of treatment in the World Health Organization (WHO) yaws eradication strategy.</p>
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