01163nas a2200229   4500000000100000008004100001653001000042653001200052653000800064653001100072100002000083700001400103700001300117700001500130700001700145245002800162856006800190300001000258490000700268520064400275022001400919       2014                            d10aPupil10aleprosy10aEye10aBrazil1 aLana-Peixoto MA1 aCampos WR1 aReis PAC1 aCampos CMC1 aRodrigues CA00aTonic pupil in leprosy.  uhttp://www.scielo.br/pdf/abo/v77n6/0004-2749-abo-77-06-0395.pdf  a395-60 v773 a<p>Pupil abnormalities in leprosy usually result from chronic iritis with loss of stroma, iris miosis, a sluggish reaction to light, and poor dilation in response to anticholinergic mydriatics. We report two patients with long-standing lepromatous leprosy who developed tonic pupils characterized by mydriasis, absence of reaction to light and hypersensitivity to weak cholinergic solution. Examination revealed iritis and iris atrophy. In both cases, instillation of dilute 0.1% pilocarpine caused miosis in the affected eyes. Tonic pupil occurs in many conditions, but its association with leprosy had not been previously reported.</p>
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