01438nas a2200229   4500000000100000008004100001653001900042653001500061653002500076653001200101100001400113700001100127700001300138700001600151700001600167245008600183856005900269300001000328490000700338520084900345022001401194       2015                            d10aRidley-Jopling10aNeuropathy10aMycobacterium leprae10aleprosy1 aBreen D P1 aDeeb J1 aVaidya S1 aLockwood DN1 aRadunovic A00aLeprosy: a 'common' and curable cause of peripheral neuropathy with skin lesions.  uhttps://www.rcpe.ac.uk/sites/default/files/breen_0.pdf  a38-420 v453 a<p>Leprosy (or Hansen's disease) is a curable chronic infectious disease caused by the acid-fast bacillus Mycobacterium leprae. While leprosy remains one of the most common causes of neuropathy worldwide, its rarity in the UK means that many doctors are unfamiliar with the typical clinical features. This is problematic because early recognition and treatment is vital in order to minimise disease-related complications such as nerve injury. We describe a 75-year-old man who presented with multiple mononeuropathy (mononeuritis multiplex, particularly affecting the ulnar nerves) and typical granulomatous skin lesions, in whom the diagnosis was made on the basis of skin biopsy. We highlight the clinical features, investigations and treatment of the patient, and provide information about the epidemiology and pathogenesis of leprosy.</p>
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