01232nas a2200241 4500000000100000008004100001653000800042653001700050653001800067100001500085700001300100700001500113700001400128700001300142700001400155700001600169245013900185856007900324300001300403490000600416520055400422022001400976 2015 d10aHIV10aEpidemiology10aCo-infections1 aPapotto PH1 aMaeda SM1 aTomimori J1 aXavier MB1 aRizzo LV1 aKallas EG1 aCarvalho KI00aNew Players in the Same Old Game: Disturbance of Group 2 Innate Lymphoid Cells in HIV-1 and Mycobacterium leprae Co-infected Patients. uhttp://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004030  ae00040300 v93 a

Leprosy control is achieved through a fine-tuning of TH1 and TH2 immune response pattern balance. Given the increasing epidemiological overlay of HIV and M. leprae infections, immune response in co-infected patients consists in an important contemporary issue. Here we describe for the first time the innate lymphoid cells compartment in peripheral blood of leprosy and HIV/M. leprae co-infected patients, and show that co-infection increases group 2 innate lymphoid whilst decreasing group 1 innate lymphoid cells frequencies and function.

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