01465nas a2200145 4500000000100000008004100001100001200042700001300054700001200067245013100079300001200210490000700222520107600229022001401305 2015 d1 aPatni V1 aBaliga S1 aSawal S00aSaliva as a Diagnostic Tool for Measurement of Total Antioxidant Capacity in Children with Leprosy and Born to Leprosy Parent. a17 - 210 v873 a
Authors' introduction:
The aim of the study is to assess the role of saliva as a diagnostic tool for measurement of total antioxidant capacity in children with leprosy and children born to leprosy parent. One hundred fifty children in the age group of 4-15 years were split into three equal groups: children with leprosy (CL) and children born to leprotic parents (CLP) and healthy children. Vitamin C level was measured in saliva of children spectrophotometrically at 695nm by Phosphomolybdenum method. Data were determined with student's unpaired t test and one way ANOVA. The result of the study showed that children with leprosy exhibited significantly decreased salivary total antioxidant capacity as compared to healthy controls. Antioxidant Vitamin C was higher in the Paucibacillary leprosy (PB) than those of Multibacillary type (MB) (P < 0.001). As age advanced, there was a gradual increase in total antioxidant capacity in both the control and study groups and the results were highly significant statistically. Saliva is an easy medium.
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