02035nas a2200193   4500000000100000008004100001100001800042700001000060700001400070700001100084700001000095700001300105245012300118856007500241300001000316490000700326520149400333022001401827       2016                            d1 aChakrabarti S1 aPal S1 aBiswas BK1 aBose K1 aPal S1 aPathak S00aClinico-Pathological Study of Cutaneous Granulomatous Lesions- a 5 yr Experience in a Tertiary Care Hospital in India.  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749196/pdf/ijp-11-054.pdf  a54-600 v113 a<p><strong>BACKGROUND: </strong>Granulomatous dermatoses are common skin pathology, often need histopathological confirmation for diagnosis. Histologically six sub-types of granulomas found in granulomatous skin diseases- tuberculoid, sarcoidal, necrobiotic, suppurative, foreign body &amp; histoid type. The aims of the present study were clinico-pathological evaluation of granulomatous skin lesions and their etiological classification based on histopathological examination.</p>

<p><strong>METHODS: </strong>It was a five years (Jan 2009- Dec 2013) retrospective study involving all the skin biopsies. Detailed clinical and histopathological features were analyzed and granulomatous skin lesions were categorized according to type of granuloma &amp; etiology. Special stains were used in few cases for diagnostic purpose.</p>

<p><strong>RESULTS: </strong>Among 1280 skin biopsies, 186 cases (14.53%) were granulomatous skin lesions with a ratio 1:24. In histopathological sub-typing, tuberculoid granuloma was most common type (126 cases, 67.74%). Most common etiology of granuloma in the study was leprosy (107 cases, 57.52%). Other etiologies were cutaneous tuberculosis, foreign body granulomas, fungal lesions, cutaneous leishmaniasis, sarcoidosis and granuloma annulare.</p>

<p><strong>CONCLUSION: </strong>Histopathology is established as gold standard investigation for diagnosis, categorization and clinico-pathological correlation of granulomatous skin lesions.</p>
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