01426nas a2200157   4500000000100000008004100001100001900042700001500061700001400076700001300090700001500103700001300118245009200131520103100223022001401254       2016                            d1 aKulshreshtha D1 aMalhotra K1 aMaurya PK1 aSingh AK1 aThacker AK1 aHusain N00aNerve biopsy in Indian patients with mononeuropathy multiplex of undetermined etiology.3 a<p><strong>INTRODUCTION: </strong>A diagnosis of mononeuropathy multiplex (MM) requires detailed evaluation to determine its etiology. We performed nerve biopsy on patients with MM in whom the etiology could not be established via other investigations.</p>

<p><strong>METHODS: </strong>68 patients with MM seen between January 2013 and June 2014 underwent detailed diagnostic evaluation. Those in whom the investigations failed to establish an etiology underwent nerve biopsy Results: The diagnosis of leprosy was confirmed in 14patients and was highly probable in 17 others. Eleven patients had vasculitic neuropathy, and in 1 patient there were amyloid deposits on nerve biopsy.</p>

<p><strong>DISCUSSION: </strong>In 43 of 68 Indian patients (63%) with MM, nerve biopsy identified a definite (26 patients) or probable (17 patients) etiology. Nerve biopsy is an important investigation in MM that frequently results in a diagnosis of leprosy in India. This article is protected by copyright. All rights reserved.</p>
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