01971nas a2200349 4500000000100000008004100001260001300042653001000055653004100065653001100106653001100117653002300128653001200151653000900163653002000172653001500192653001500207653002600222653003100248100001100279700001000290700001200300700000900312700001100321245010200332856005100434300001100485490000700496050003200503520107200535022001401607 2006 d c2006 Sep10aChina10aDrug Resistance, Multiple, Bacterial10aFemale10aHumans10aLeprostatic Agents10aleprosy10aMale10aMedical Records10aPrevalence10aRecurrence10aRetrospective Studies10aSurveys and Questionnaires1 aShen J1 aLiu M1 aZhang J1 aSu W1 aDing G00aRelapse in MB leprosy patients treated with 24 months of MDT in south west China: a short report. uhttps://leprosyreview.org/article/77/3/21-9224 a219-240 v77 aInfolep Library - available3 a

This study investigates the relapse rate among multibacillary leprosy patients treated with 24 months of MDT in south west China. A retrospective relapse survey was conducted in the southwest of China. A detailed questionnaire was designed to collect the data on relapse among MB patients who completed 2 years of the WHO/MB regimen, from 1989 to 2000. The data about 2517 multibacillary leprosy patients in 27 counties in the southwest of China were collected. Among 2517 MB patients, 235 patients died or were lost to follow-up and 2374 were followed up for more than 3 years after completion of MDT. The total duration of follow-up was 20,825 person-years, with a mean duration of 8.27 years per patient. Five patients with relapse were identified with an accumulated relapse rate of 0.21/1000 person-years. Their initial BIs ranged from 1.8 to 5. The patients with relapse occurred 48-158 months after the completion of MDT. The relapse rate of MB patients treated with 24 months of the WHO/MB regimen was observed to be very low after long-term follow-up.

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