02276nas a2200421 4500000000100000008004100001653003900042653002400081653001400105653002400119100001500143700001400158700001500172700001500187700001400202700001100216700001200227700001600239700001300255700001300268700001300281700001200294700001600306700001300322700002200335700001400357700001300371700001600384700001500400700001500415700001400430245011700444856008800561300001300649490000700662520117100669022001401840 2016 d10aNeglected tropical diseases (NTDs)10aHelminth infections10adiagnosis10aAccess to treatment1 aAlbonico M1 aBecker SL1 aOdermatt P1 aAngheben A1 aAnselmi M1 aAmor A1 aBarda B1 aBuonfrate D1 aCooper P1 aGétaz L1 aKeiser J1 aKhieu V1 aMontresor A1 aMuñoz J1 aRequena-Méndez A1 aSavioli L1 aSpeare R1 aSteinmann P1 aLieshout L1 aUtzinger J1 aBisoffi Z00aStrongNet: an international network to improve diagnostics and access to treatment for Strongyloidiasis control. uhttp://journals.plos.org/plosntds/article/asset?id=10.1371/journal.pntd.0004898.PDF ae00048980 v103 a

Strongyloidiasis is a disease caused by an infection with a soil-transmitted helminth that affects, according to largely varying estimates, between 30 million and 370 million people worldwide [1,2]. Not officially listed as a neglected tropical disease (NTD), strongyloidiasis stands out as particularly overlooked [3]. Indeed, there is a paucity of research and public health efforts pertaining to strongyloidiasis. Hence, clinical, diagnostic, epidemiologic, treatment, and control aspects are not adequately addressed to allow for an effective management of the disease, both in clinical medicine and in public health programs [4]. The manifold signs and symptoms caused by Strongyloides stercoralis infection, coupled with the helminth’s unique potential to cause lifelong, persistent infection, make strongyloidiasis relevant beyond tropical and subtropical geographic regions, where, however, most of the disease burden is concentrated. Indeed, strongyloidiasis is acquired through contact with contaminated soil, and the infection is, thus, primarily transmitted in areas with poor sanitation, inadequate access to clean water, and lack of hygiene.

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