01478nas a2200217   4500000000100000008004100001653002100042653001100063653001500074653001900089653001200108653004500120100001100165700001200176700001300188245006200201856003300263300001000296490000600306520094800312       2018                            d10aDapsone syndrome10aDengue10aInfections10aLepra reaction10aleprosy10aMultibacillary multidrug therapy (MBMDT)1 aKaur J1 aKalsy J1 aKalra RK00aInfections and reactions in leprosy: a diagnostic dilemma  uhttps://tinyurl.com/ybwlpuwx  a96-980 v43 a<p>Leprosy (Hansen’s disease) is a chronic infectious disease caused by <em>Mycobacterium leprae</em>. It continues to be a public health problem in India, which contributes about 60% to the world leprosy burden. Leprosy patients when on treatment can develop either lepra reactions or reactions due to antileprosy drugs, also they can develop other infections endemic in their areas during the course of their disease. We are presenting such two cases where in one case patient on treatment with multibacillary multidrug therapy (MBMDT) developed fever, lympadenopathy and other systemic features during the course of therapy and was mistakenly diagnosed as type 2 lepra reaction but turned out to be a case of dapsone hypersensitivity. Similarly another case developed fever and other systemic features after 6 weeks of MBMDT, thinking it to dapsone syndrome his MBMDT pack was stopped but later it turned out to be a case of dengue.</p>