01309nas a2200217 4500000000100000008004100001653001200042653002400054653001300078653003000091653001800121653002000139653002700159100001300186700001500199245004900214856008300263300000800346490000600354520073100360 2017 d10aleprosy10aClinical immunology10aImmunity10aImmunological alterations10aT lymphocytes10aPathophysiology10aImmunological problems1 aJadue FR1 aGuevara JA00aImmunological aspects of Hansen’s Disease. uhttps://pdfs.semanticscholar.org/9652/8edcd60362d2ebf74be82a35d0818525cd86.pdf a1-40 v63 a
Considering the complexity of the clinical manifestations of Hansen’s Disease and its correlation with the immunological alterations found within the clinical aspect of the disease. Leprae defense is the response to cell-mediated immunity, especially macrophages and T lymphocytes, which by means of the effective interaction of their activities, may or may not destroy the bacilli. All the evolution and pathophysiology of the disease may be related to the immunological alterations of the parasite - host reaction that occurs in leprosy. After the presentation of the characteristic immunological problems and their correlation with the clinical forms they become fundamental for the understanding of the disease.