00816nas a2200169 4500000000100000008004100001100001600042700001300058700001700071700001500088245010100103856005900204300001400263490000700277520034800284022001400632 2018 d1 aWilliams DL1 aAraujo S1 aStryjewska B1 aScollard D00aDapsone resistance in leprosy patients originally from American Samoa, United States, 2010-2012. uhttps://wwwnc.cdc.gov/eid/article/24/8/18-0033_article a1584-15850 v243 a

Skin biopsies from US leprosy patients were tested for mutations associated with drug resistance. Dapsone resistance was found in 4 of 6 biopsies from American Samoa patients. No resistance was observed in patients from other origins. The high rate of dapsone resistance in patients from American Samoa warrants further investigation.

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