01155nas a2200145   4500000000100000008004100001653001200042653001700054653002300071100001300094245006000107856005700167300001200224520077300236       2018                            d10aleprosy10aTuberculosis10aHensen’s disease1 aSubedi R00aAn Overview Background of Hensen’s Disease or Leprosy  uhttps://www.ecronicon.com/ecmi/pdf/ECMI-14-00513.pdf  a438-4433 a<p>Leprosy is a granulomatous disease acquired by the <em>Mycobacterium leprae</em>. Although there is a significant improvement in the treatment of this disease, it is still endemic in many regions, commonly in India, Indonesia, Brazil and many other nations. The pathogenesis of the bacteria is full of complexity and it has remained to be elucidated. The clinical presentation of the disease based on the patient’s immune system. Surprisingly, leprosy is a type disease which diagnosis can only be processed when one of the clinical signs described by WHO (discussed below) has appeared in infected patients. Like tuberculosis, leprosy is also treated with multidrug therapy. Moreover, the future directions of the leprosy were also discussed in this paper.</p>