01278nas a2200193   4500000000100000008004100001653002000042653002100062653002100083653001200104100001300116700001500129700001800144700001700162245005700179856005900236300001200295520077700307       2018                            d10aCorticosteroids10aDapsone syndrome10aHypersensitivity10aleprosy1 aSwetha S1 aVyshnavi P1 aGeethanjali K1 aNedamanuru K00aA Case Report on Dapsone Syndrome in Leprosy Patient  uhttps://www.ecronicon.com/ecprm/pdf/ECPRM-07-00234.pdf  a522-5243 a<p>Dapsone is a sulfone group of drug with anti-inflammatory and antibiotic properties. It is the cheapest, oldest and most active drug in sulfone family used in treatment of leprosy and skin blistering diseases. Dapsone causes several adverse reactions among which some are fatal with multiorgan involvement such as dapsone hypersensitivity syndrome or dapsone syndrome. Prompt diagnosis, drug discontinuation and early treatment is essential to prevent its fatal effects and associated mortality. We report a case of 35 year old male with complaints of fever, tightness and scaling all over the body after dapsone administration. Patient was improved and discharged on treating with corticosteroids, antihistamines, antibiotics, emollients and vitamin supplements.</p>