02059nas a2200253   4500000000100000008004100001653001200042653002100054653002400075653001900099653001600118653001600134653001300150100001900163700001700182700001800199700002000217700001900237245011400256856007800370300001200448490000700460520133800467       2018                            d10aleprosy10aDrug information10aIrrational drug use10aLepra reaction10aClofazimine10aThalidomide10aSteroids1 aPugazhenthan T1 aVenkatesan S1 aTamilselvan T1 aSivashanmugam E1 aShowkath Ali M00aInformation on Drugs Used in Management of Lepra Reactions in Commonly used Drug Information Sources in India  uhttp://www.ijl.org.in/2018/5%20T%20Pugazhenthan%20et%20al%20(129-136).pdf  a129-1360 v903 a<p>Availability of adequate and proper drug information helps in rational prescription of essential drugs. This can be obtained from various sources such as National Formularies; other sources such as Current Index of Medical Specialties, Monthly index of medical specialties and the information available with the regulators and drug package inserts (PI). In this study, we assessed the drug information of the drugs used for treatment of both type of lepra reactions. Five drugs used for treating Lepra reactions were analyzed for any variation (Qualitative) in information on various parameters as mentioned in commonly used drug information sources such as CIMS India, MIMS India, Central Drugs and Standards Control Organization (CDSCO) website and National Formulary of India (NFI). We observed some gross qualitative variation regarding drug information given in different commonly used sources. Variation exists in the quality of information available on indications, contraindications, dosage and completeness of the dosing schedule about drugs available in various sources. As management of Lepra reactions is crucial in achievement desirable outcome of treatment of leprosy, it is important that information regarding drugs used for such indications should be 100% uniform in all commonly used and available sources.</p>