01770nas a2200373 4500000000100000008004100001260001700042653001000059653004200069653001200111653002500123653002800148653001100176653001800187653001900205653001100224653001000235653001200245653000900257653002200266653001400288653001800302653001300320653002800333653001500361100001200376700001300388700001300401245011100414300001100525490000700536520083900543022001401382 2008 d c2008 May-Jun10aAdult10aAIDS-Related Opportunistic Infections10aAnimals10aCD4 Lymphocyte Count10aDiagnosis, Differential10aFemale10aHerpes Zoster10aHIV Infections10aHumans10aIndia10aleprosy10aMale10aMite Infestations10aPrognosis10aSkin Diseases10aSyndrome10aTuberculosis, Cutaneous10aViral Load1 aHanda S1 aNarang T1 aWanchu A00aDermatologic immune restoration syndrome: report of five cases from a tertiary care center in north India. a126-320 v123 a

BACKGROUND: Dermatologic conditions are often an early clue to human immunodeficiency virus (HIV) infection. As the disease progresses and the host immunity fails, patients may develop a number of skin conditions. At this point, they have a dominant T helper 2 immunologic response. After the initiation of antiretroviral therapy, the T helper 1 response is restored, and some skin problems, paradoxically, make their appearance then.

CONCLUSION: Herpes zoster, mucocutaneous herpes, eosinophilic folliculitis, and mycobacterial infections have been known to occur at this stage. This may be because immune restoration of a host's immunity causes recognition of silent or latent infection and results in development of the condition. We report five cases that were seen at our center during a 2-year period.

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