02127nas a2200301 4500000000100000008004100001260001300042653001900055653002300074653001000097653001000107653001100117653001000128653001200138100001400150700001200164700002100176700001300197700001400210700001500224700001500239245009900254856004100353300000900394490000700403520140100410022001401811 2005 d c2005 Jun10aHIV Infections10aHIV Seroprevalence10aHIV-110aHIV-210aHumans10aIndia10aleprosy1 aHussain T1 aSinha S1 aKulshreshtha K K1 aKatoch K1 aYadav V S1 aSengupta U1 aKatoch V M00aSeroprevalence of HIV infection among leprosy patients in Agra, India: trends and perspective. uhttp://ila.ilsl.br/pdfs/v73n2a02.pdf a93-90 v733 a

This study compares the results of HIV seroprevalence, which was carried out in two phases, i.e., 1989 to 1993 and 1999 to 2004. Although the number of leprosy patients screened for HIV infection in the second phase is less (2125) as compared to those screened during the first phase (4025), a rise in HIV infection from 0.12% to 0.37% is certainly disturbing since this area appears to be endemic for both the infections. During the study period, the Out Patient department attendance of a few types of leprosy patients like borderline and borderline lepromatous have risen, whereas others like borderline tuberculoid and polar tuberculoid have declined in the second phase as compared to that of the first phase. The trend over a decade suggests that HIV infection is low among the leprosy patients when compared with other risk groups. Follow-up of these patients at an interval of six months, revealed that none of them downgraded into a severe form of leprosy nor developed ARC or AIDS. In this study, it appears that neither infection precipitated the other. The occurrence of downgradation as well as reversal reactions and neuritis (both chronic and acute) was not observed among the leprosy patients. None of them developed erythema nodosum leprosum reactions. Similarly, the HIV-positive leprosy cases did not develop either AIDS related complex (ARC) or full blown case of AIDS.

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