01290nas a2200277 4500000000100000008004100001260001700042653001000059653001100069653001100080653002500091653002500116653002500141653001800166653002200184653001800206100001200224700001800236700001700254245008800271300000900359490000700368050003200375520059100407022001400998 1992 d c1992 Jan-Mar10aAxons10aBiopsy10aHumans10aLeprosy, lepromatous10aLeprosy, Tuberculoid10aMicroscopy, Electron10aMyelin Sheath10aPeripheral nerves10aSchwann Cells1 aKumar V1 aNarayanan R B1 aMalaviya G N00aAn ultrastructural study of Schwann cells in peripheral nerves of leprosy patients. a81-70 v64 aInfolep Library - available3 a

An ultrastructural study of peripheral nerves in leprosy patients was carried out of ascertain the changes in Schwann cells containing myelinated and nonmyelinated axons. Axonal multiplication was noticed in nonmyelinated axons in specimens from both tuberculoid and lepromatous leprosy. The Schwann cells in tuberculoid nerves were devoid of M. leprae in contrast to those in lepromatous nerves in which large number of bacilli were seen. These observations suggest that the Schwann cells containing nonmyelinated axons may be affected more frequently in either type of leprosy.

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