01531nas a2200253   4500000000100000008004100001260001700042653001000059653001100069653001200080653001100092653002500103653000800128653000900136653001700145653001100162653000900173100001500182245008500197300000900282490000700291520096500298022001401263       2005                            d  c2005 Jan-Mar10aCheek10aFemale10aGingiva10aHumans10aLeprosy, lepromatous10aLip10aMale10aMouth Mucosa10aPalate10aSkin1 aPalaskar S00aHistopathological study of apparently normal oral mucosa in lepromatous leprosy.  a12-40 v163 a<p>In lepromatous leprosy, it may be postulated that apparently normal areas of skin are the probable sites of future extension of the pathological process and the events taking place in these site might represent the earlier stages of such an extension. Thus the present study has been done to evaluate any such changes in the apparently normal oral mucous membrane of the lepromatous leprosy patients, since oral involvement is common in these patients. Twenty two cases of lepromatous leprosy were studied histologically to see changes in apparently normal oral mucosa. Out of the 22 patients, apparently normal skin biopsies were taken from 13 patients and 5 lesional biopsies were taken from the same patients. Apparently normal oral mucosal biopsies were done for all patients. Biopsies of 22 cases of apparently normal oral mucosa did not show granulation formation of acid-fast bacilli histologically. The only change present was mild inflammation.</p>  a0970-9290