01212nas a2200313   4500000000100000008004100001260001300042653001700055653001100072653001400083653001100097653002500108653001300133653000900146653000900155653001800164653001700182100001300199700001400212700001200226700001300238700001200251700001400263245007000277300001100347490000600358520052000364022001400884       1991                            d  c1991 May10aAntigens, CD10aFemale10aGranuloma10aHumans10aImmunohistochemistry10aLepromin10aMale10aSkin10aSkin Diseases10aTime Factors1 aFujita M1 aMiyachi Y1 aIzumi S1 aIshida H1 aObara A1 aImamura S00aImmunohistochemical study of lepromin reaction in healthy adults.  a179-820 v23 a<p>Lepromin reaction was studied with immunoperoxidase techniques using monoclonal antibodies. The skin reactions were induced by injecting Mitsuda antigen into healthy adults without a family history of leprosy. Both early (48 hours) and late (3 weeks and 2 months) reactions were examined. In the late reaction, focal collections of epithelioid cells had formed, and not only T- but also B-lymphocytes were observed around the granuloma. CD1a+ cells were also confirmed to have increased in the late reaction.</p>  a0923-1811