01448nas a2200217   4500000000100000008004100001260001200042653001700054653001200071653002500083100001500108700001500123700001200138700001500150245006100165856008300226300001200309490000700321520088800328022001401216       2019                            d  c01/201910aEpidemiology10aleprosy10aMycobacterium leprae1 aSouza CDFD1 aSantos FGB1 aLeal TC1 aPaiva JPSD00aTrend of leprosy detection rate in Brazil, 1990 to 2016.  uhttps://www.sciencedirect.com/science/article/pii/S0365059619300480?via%3Dihub  a603-6070 v943 a<p>The objective of this study was to describe the trend of detection of the disease in Brazil from 1990 to 2016. The joinpoint regression model was used. There was a significant trend of decreased detection in the country (average annual percent change -1.8%) and in the South (average annual percent change=-3.5%) and Southeast regions (average annual percent change=-4.5%). The Northeast (average annual percent change=0.2%), the Central-West (average annual percent change=-1.5%), and the North (average annual percent change=-2.6%) showed a stationary trend (p>0.05). Eleven states showed a decreasing trend. Alagoas (average annual percent change=2.1%) and Rio Grande do Norte (average annual percent change=1.4%) presented significant increase (p<0.001). The heterogeneous pattern of trend between regions and states shows that efforts are needed to eliminate the disease.</p>  a1806-4841