01210nas a2200193   4500000000100000008004100001100001400042700001400056700001200070700001200082700001200094700001500106700001500121245011800136856005100254300001400305490000700319520069000326       2019                            d1 aLavania M1 aDarlong J1 aReddy A1 aAhuja M1 aSingh I1 aTurankar R1 aSengupta U00aSuccessful treatment of rifampicin resistant case of leprosy by WHO recommended ofloxacin and minocycline regimen  uhttps://leprosyreview.org/article/90/4/19-0059  a456–4590 v903 aA 25-year-old male treated for leprosy at the age of 15, with MDT, visited TLM Purulia Hospital in July 2017. He was provisionally diagnosed as a lepromatous relapse with ENL reaction. A biopsy was done to test for drug resistance. Drug resistance testing showed resistance to rifampicin. Second line drug regimen recommended by WHO for rifampicin-resistance was started. Within 6 months of taking medication the clinical signs and symptoms improved rapidly and the BI dropped by 1·66 log within 6 months. This case highlights the need for investigations in cases of relapse and the efficacy of WHO recommended second line drug regimen treatment in rifampicin-resistant leprosy cases.