01159nas a2200169   4500000000100000008004100001260001200042100001400054700001100068700001300079245008400092856010600176300001400282490000700296520067200303022001400975       2019                            d  c01/20191 aOlivier M1 aModi D1 aGunduz O00aDe novo Histoid leprosy: an expatriate case recently diagnosed in Johannesburg.  uhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100701&lng=en&nrm=iso&tlng=en  ae201904680 v533 a<p>Histoid leprosy (HL) is a rare variant of lepromatous leprosy with unique clinical, histopathological, and microbiological features. A 32-year-old man from Malawi who immigrated to Johannesburg 1-year-ago, presented with a 4-month history of flesh-colored nodules on the face and trunk and hyperpigmented plaques on the chest and limbs. Skin slit smears confirmed multibacillary leprosy, and skin punch biopsies showed proliferation of spindled cells containing a large number of acid-fast bacilli. The prevalence of de novo HL is increasing in the era of leprosy elimination. HL cases may act as reservoirs and negatively affect the global control of leprosy.</p>  a1678-9849