03342nas a2200649 4500000000100000008004100001653001600042653001500058653003300073653004500106653001200151100001900163700001600182700001200198700001200210700001100222700001000233700001100243700001600254700001400270700001400284700001800298700001800316700001200334700001000346700001500356700001500371700001100386700001300397700001400410700001300424700001300437700001200450700001200462700001000474700001300484700001200497700001500509700001300524700001300537700001700550700001700567700001300584700001600597700002000613700001100633700001300644700001900657700001700676700001400693700001400707700001600721245010700737300001200844490000600856520183000862 2020 d 10 aProphylaxis 10 aRifampicin 10 aSingle-dose rifampicin (SDR) 10 aLeprosy Post-Exposure Prophylaxis (LPEP) 10 aToolkit 1 aBarth-Jaeggi T 1 aCavaliero A 1 aAerts A 1 aAnand S 1 aArif M 1 aAy SS 1 aAye TM 1 aBanstola NL 1 aBaskota R 1 aBlaney DD 1 aBonenberger M 1 avan Brakel WH 1 aCross H 1 aDas V 1 aBudiawan T 1 aFernando N 1 aGani Z 1 aGreter H 1 aIgnotti E 1 aKamara D 1 aKasang C 1 aKömm B 1 aKumar A 1 aLay S 1 aMieras L 1 aMirza F 1 aMutayoba B 1 aNjakov B 1 aPakasi T 1 aRichardus JH 1 aSaunderson P 1 aSmith CS 1 aStähelik R 1 aSuriyarachchi N 1 aShwe T 1 aTiwari A 1 aWijesinghe MSD 1 avan Berkel J 1 aPlaetse B 1 aVirmond M 1 aSteinmann P 00 aProfilaxis post-exposición para lepra con dosis única de rifampicina: manual para su implementación a263-272 0 v4 3 aObjective: Leprosy post-exposure prophylaxis with single-dose rifampicin (SDRPEP)
has proven effective and feasible, and is recommended by WHO since 2018. This SDR-PEP toolkit was developed
through the experience of the leprosy post-exposure prophylaxis (LPEP) programme. It has been designed to
facilitate and standardise the implementation of contact tracing and SDR-PEP administration in regions and
countries that start the intervention.
Results: Four tools were developed, incorporating the current evidence for SDRPEP and the methods and learnings
from the LPEP project in eight countries. (1) the SDR-PEP policy/advocacy PowerPoint slide deck which will help
to inform policy makers about the evidence, practicalities and resources needed for SDR-PEP, (2) the SDR-PEP field
implementation training PowerPoint slide deck to be used to train front line staff to implement contact tracing
and PEP with SDR, (3) the SDR-PEP generic field guide which can be used as a basis to create a location specific
field protocol for contact tracing and SDR-PEP serving as a reference for frontline field staff. Finally, (4) the SDR-PEP
toolkit guide, summarising the different components of the toolkit and providing instructions on its optimal use.
Conclusion: In response to interest expressed by countries to implement contact tracing and leprosy PEP with SDR
in the light of the WHO recommendation of SDRPEP, this evidence-based, concrete yet flexible toolkit has been
designed to serve national leprosy programme managers and support them with the practical means to translate
policy into practice. The toolkit is freely accessible on the Infolep homepages and updated as required:
https://www.leprosy-information.org/keytopic/leprosy-post-exposure-prophylaxis-lpep-programme