01189nas a2200253   4500000000100000008004100001260001200042653000800054653001000062653002000072653001200092100001500104700001400119700001300133700001600146700001500162700001500177700001600192700001300208700001600221245005300237520063100290022001400921       2020                            d  c06/202010aHLA10aHLA-G10aImmune response10aleprosy1 ada Silva C1 aSampaio L1 aCosta MB1 aCysneiros M1 aSadissou I1 aCastilho M1 ade Moraes J1 aDonadi E1 aWastoswki I00aAnalysis of HLA-G protein expression in leprosy.3 a<p>The aim of this study was to evaluate the expression of human leukocyte antigen G (HLA-G) in leprosy. Biopsy and serum samples were collected from 18 patients presenting with leprosy and from healthy controls. Samples were analyzed using immunohistochemistry and ELISA techniques. HLA-G expression was observed in biopsy samples of all patients. The healthy control samples were consistently negative for HLA-G expression. Control plasma samples displayed significantly higher HLA-G expression than those from the patients (p < 0.01). These results are the first demonstration of the expression of HLA-G in leprosy.</p>  a1432-1211