01039nas a2200169   4500000000100000008004100001260001000042100001300052700001500065700001100080245008200091856005100173300001200224490000700236520061200243022001400855       2020                            d  bLepra1 aNarang I1 aAilawadi P1 aGarg V00aUncommon adverse effects of thalidomide: seldom reported phenomena in leprosy  uhttps://leprosyreview.org/article/91/2/19-0080  a200-2030 v913 aThe efficacy of thalidomide has been a landmark in the treatment of ENL, especially the severe forms like ENL necroticans. Thalidomide does have its share of adverse effects (AE), but with the low doses used in leprosy, we do not encounter very severe AEs, seen with its use in myeloid malignancies and other illnesses. We describe here a case of ENL treated with thalidomide and subsequent development of some seldom reported severe AE like pancytopenia and severe neuropsychriatric symptoms. Such features of drug toxicity must be taken into consideration while monitoring a patient of ENL on thalidomide.  a2162-8807