01187nas a2200181   4500000000100000008004100001260001200042653001600054653003100070100001500101700001700116700001400133700001500147245010300162856008300265520064300348022001400991       2021                            d  c01/202110aClofazimine10aDapsone leprosy rifampicin1 aTortelly V1 aDaxbacher EL1 aBrotas AM1 aCarneiro S00aAdverse effects of polychemotherapy for leprosy in 13 years of follow-up at a university hospital.  uhttps://www.sciencedirect.com/science/article/pii/S0365059621000039?via%3Dihub3 a<p>Leprosy is one of the neglected diseases in the world and Brazil is the second country with more cases. A retrospective study was conducted based on the medical records of 196 leprosy patients diagnosed during the course of 13 years at a university hospital. The aim was to describe the adverse effects of polychemotherapy, as well the most prevalent and most vulnerable populations. In the study, dapsone was the most implicated drug, especially in women, and the risk increased with age. The authors conclude that with this patient profile, greater vigilance should be taken regarding possible adverse effects, especially anemia.</p>  a1806-4841