01537nas a2200193   4500000000100000008004100001260001200042653001600054653000800070653001500078100001300093700001300106700001200119700001200131245007400143490000700217520110500224022001401329       2022                            d  c01/202210aDermatology10aEye10aInfections1 aSarkar D1 aChawla H1 aSingh P1 aVerma V00aCase of leprosy mimicking preseptal cellulitis: a diagnostic dilemma.0 v153 a<p>A 36-year-old Asian man presented with swelling over the left frontal region involving the upper eyelids, with associated erythema and tenderness for 1 month duration. Clinically he was diagnosed as a case of preseptal cellulitis, however, the lesion did not improve on broad-spectrum systemic antibiotics. CT showed superficial soft tissue swelling in the forehead extending till the superior part of orbit. Histopathological assessment of the lesion revealed clusters of epithelioid cells with multinucleate giant cells in the dermis along with perivascular and periadnexal lymphocytic infiltrates, suggestive of leprosy. The patient was started on oral steroids with multidrug therapy, following which the patient showed early resolution of the lesion within 10 days of treatment. Leprosy is endemic in India, leprosy with reactional episodes mimics other inflammatory and infective etiologies making diagnosis difficult. Leprosy should be present in an ophthalmologist's diagnostic repertoire while dealing with periorbital swellings for early clinical diagnosis and favourable outcomes.</p>
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