01202nas a2200241 4500000000100000008004100001260001200042653001400054653002100068653001200089653002500101100001600126700001400142700001500156700001400171700001500185245008200200856007000282300001100352490000700363520057600370022001400946 2022 d c01/202210aArthritis10aErythema Nodosum10aleprosy10aMycobacterium leprae1 aGoulart IMB1 aSantana M1 ada Costa W1 aPavelka M1 aDornelas B00aType 2 leprosy reaction presenting as a monoarthritis post multidrug therapy. uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749206/pdf/main.pdf ae013860 v273 a

Type 2 leprosy reaction, or (ENL), involves a complex interaction between the host's immune system and . It may occur before, during, or after treatment and have a variable clinical presentation involving different body systems, such as skin, osteoarticular, kidneys, and others. Thus, the differential diagnosis, depending on its clinical presentation, can be broad and challenging. The authors report a case of a severe monoarthritis during a type 2 reaction after the multidrug therapy (MDT) was discharged and the investigation of the differential diagnoses.

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